Only comments seeking to improve the quality and accuracy of information on the Orphanet website are accepted. For all other comments, please send your remarks via contact us. Only comments written in English can be processed. A rare predominantly large-vessel vasculitis that is characterized by affected aorta and its major branches, but also other large vessels, causing stenosis, occlusion, or aneurysm. Takayasu arteritis TAK prevalence has been estimated to be 13 to 40 per million habitants.

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It may also affect the pulmonary arteries. The exact cause is not well known but the pathology is thought to be similar to giant cell arteritis.

The typical age of onset is at around years of age. It induces clinically varied ischemic symptoms due to stenotic lesions or thrombus formation. The exact spectrum can be highly variable and dependent on the territory of vascular involvement. There is segmental and patchy granulomatous inflammation of the aorta which results in stenosis, thrombosis and aneurysm formation.

The initial systemic illness may include symptoms of malaise, fever, night sweats, weight loss and arthralgia. There is often anemia with raised inflammatory markers. This phase gradually resolves with the initiation of the chronic phase which is characterized by inflammatory and obliterative changes in the aorta and its branches.

There are often reduced or absent peripheral pulses, giving rise to its alternative name of "pulseless disease". The pulmonary arteries are also commonly involved, with the most common appearance being peripheral pruning.

Described features on CTCA include 7 :. Treatment is with systemic steroids and judicious use of angioplasty. Corticosteroids can be used for initial treatment. Other medical options include methotrexate, cyclophosphamide, and cyclosporine. Percutaneous angioplasty and bypass surgery should only be considered when there is no acute inflammation.

Prognosis tends to be variable ranging from a rapidly progressive disease in some reaching a quiescent stage in others. The condition is named after Dr. Please Note: You can also scroll through stacks with your mouse wheel or the keyboard arrow keys. Updating… Please wait. Unable to process the form. Check for errors and try again.

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Arterite de Takayasu

The Portuguese Journal of Cardiology, the official journal of the Portuguese Society of Cardiology, was founded in with the aim of keeping Portuguese cardiologists informed through the publication of scientific articles on areas such as arrhythmology and electrophysiology, cardiovascular surgery, intensive care, coronary artery disease, cardiovascular imaging, hypertension, heart failure and cardiovascular prevention. The Journal is a monthly publication with high standards of quality in terms of scientific content and production. Since it has been published in English as well as Portuguese, which has widened its readership abroad. It is distributed to all members of the Portuguese Societies of Cardiology, Internal Medicine, Pneumology and Cardiothoracic Surgery, as well as to leading non-Portuguese cardiologists and to virtually all cardiology societies worldwide.


Takayasu's arteritis

Chauhan et al. Verma et al. Tripathy et al. Segundo Sheikhzadeh et al. Para Salvarani et al. Park et al. Maksimowicz-McKinnon et al.

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