Water intoxication-a dangerous condition in labor and delivery rooms. Obstet Gynecol Surv ; Maternal water intoxication as a cause of neonatal seizures. J Paediatr Child Health ; Buchan PC.

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Figueroa D. Osteomalacia inducida por tumor: hemangiopericitoma rinosinusal. Directory of Open Access Journals Sweden. Pinto Filho, S.

Fractalkine depresses cardiomyocyte contractility. Gene array on left ventricles LV showed increased fractalkine, a chemokine implicated in heart failure. We therefore hypothesized that fractalkine is regulated by PGE2 and contributes to depressed contractility via alterations in intracellular calcium.

The effect of fractalkine on contractility and intracellular calcium was determined in Fura-2 AM-loaded, electrical field-paced cardiomyocytes. Fractalkine treatment of AVM decreased both the speed of contraction and relaxation under basal conditions and after Iso stimulation.

Fractalkine depresses myocyte contractility by mechanisms downstream of intracellular calcium. Agranulocitosis inducida por metimazol en pacientes con enfermedad de Graves.

Al ingreso, todos los pacientes presentaron fiebre y dolor de garganta. En todos los casos, el tratamiento definitivo fue yodo radioactivo. Osteoporosis secundaria y Osteoporosis inducida por glucocorticoides OIG. Las malformaciones vasculares uterinas son muy infrecuentes y se presentan asociadas a metrorragia con riesgo vital. Su incidencia no es conocida porque las series son de pocos casos.

Otras dos pacientes, p Structural comparison of contractile nanomachines. Full Text Available Contractile molecular machines are a common feature among bacteriophages and prokaryotes.

Due to their stability and the large size, contractile -tailed bacteriophages are traditionally investigated by electron microscopic methods. Complemented by crystallographic studies, a molecular model of contraction for the T4 phage was developed.

Lately, also related contractile structures like the Photorhabdus virulence cassette-like particles, the R-Type pyocins and the contractile tubule of the bacterial Type VI secretion system have been analyzed by cryo electron microscopy. Photorhabdus virulence cassette particles and R-Type pyocins are toxin complexes reminiscent of bacteriophage tails that are secreted by bacteria to kill their insect host or competing bacteria.

In contrast, the Type VI secretion system is an intracellular apparatus for injection of effector proteins into bacterial and eukaryotic cells. Although it shares homology with other contractile systems, the Type VI secretion system is additionally equipped with a recycling function, which makes it suitable for multiple rounds of action.

Starting from the 3D reconstructions, we compare these molecular machines structurally and functionally to their viral counterparts and summarize the current knowledge on their respective mode of action. Conclusiones de los autores: Las pruebas actualmente disponibles son muy limitadas. Full Text Available Trolox is a hydrophilic analogue of vitamin E and a free radical scavenger.

Ethanol diminishes the amplitude of spontaneous contractions and acetylcholine ACh-induced contractions in rabbit duodenum. The aim of this work was to study the effect of Trolox on the alterations induced by ethanol on contractility and lipid peroxidation in the duodenum.

Trolox increased the reduction induced by ethanol on the amplitude of spontaneous contractions in longitudinal muscle but not in circular muscle. We conclude that Trolox might prevent oxidative stress induced by ethanol in the duodenum. Modulatory effects of taurine on jejunal contractility.

Full Text Available Taurine 2-aminoethanesulfonic acid is widely distributed in animal tissues and has diverse pharmacological effects. However, the role of taurine in modulating smooth muscle contractility is still controversial. We propose that taurine mM can exert bidirectional modulation on the contractility of isolated rat jejunal segments.

Different low and high contractile states were induced in isolated jejunal segments of rats to observe the effects of taurine and the associated mechanisms. Taurine induced stimulatory effects on the contractility of isolated rat jejunal segments at 3 different low contractile states, and inhibitory effects at 3 different high contractile states.

The stimulatory effects of taurine on the contractility of isolated jejunal segments was blocked by atropine but not by diphenhydramine or by cimetidine, suggesting that muscarinic-linked activation was involved in the stimulatory effects when isolated jejunal segments were in a low contractile state.

No bidirectional effects of taurine on myosin phosphorylation were observed. Yao, Q. Taurine 2-aminoethanesulfonic acid is widely distributed in animal tissues and has diverse pharmacological effects. Describes an experiment using rats that demonstrates contractile characteristics of normal and hypertrophied muscle. Compensatory hypertrophy of the plantaris muscle is induced by surgical removal of the synergistic gastrocnemium muscle.

Includes methods for determination of contractile properties of normal and hypertrophied muscle and…. Full Text Available Obstetrical emergencies are problem in veterinary clinics and hospital. So, the aim of this report is to describe the clinical-surgical aspect of one of them, the uterine prolapse. Complete protrusion and retroflexion of uterus had been diagnosed in a queen and female dog, respectively. After the stabilization of the animals and reduction of the prolapses followed by ovary-hysterectomy, one of the animals came to death due to septicemia and hypovolemic shock.

Rapid assessment and intensive treatments are required to sustain the life of the animal. Verificou-se efeito de tempo P0, Osteomalacia inducida por tumor: hemangiopericitoma rinosinusal Tumor-induced osteomalacia: rhinosinusal hemangiopericytoma.

Tumor-induced osteomalacia is a rare disease of bone metabolism. The characteristic of this disease is an increase in phosphate excretion followed by hypophosphatemia, due to phosphaturic agents produced by different types of tumors. Tumor resection results in complete resolution of clinical, biochemical and radiological abnormalities. We present the case of a 61 year old man with signs, symptoms and laboratory findings consistent with oncogenic osteomalacia due to a rhino-sinusal mesenchymal tumor.

The histological diagnosis showed a vascular neoplasm: hemangiopericytoma. Spontaneous Uterine Rupture in Second Trimester of Pregnancy: Case report and Literature review Abstract Uterine rupture is a solution of continuity of the uterine wall.

It is an uncommon and potentially lethal obstetric complication, for both mother and fetus, that mainly occurs during the second or third trimester of pregnancy, and that is mainly associated to previous uterine surgery, thus forming a medical challenge for its difficult differential diagnosis and controversial management.

We report the case of a 26 years old patient with a spontaneous gravid uterine rupture, 18 weeks of gestation and cesarean scar background. Laparotomy is conducted finding both placenta and umbilical cord attached to no-living fetus in the abdominal cavity, which confirms intraoperative diagnosis.

El reporte de biopsia de dichas piezas operatorias resultaron negativas para malignidad. La paciente se encuentra actualmente libre de enfermedad. These tumors usually appear in women. Actomyosin contractility rotates the cell nucleus. The cell nucleus functions amidst active cytoskeletal filaments, but its response to their contractile stresses is largely unexplored.

We study the dynamics of the nuclei of single fibroblasts, with cell migration suppressed by plating onto micro-fabricated patterns. We find the nucleus undergoes noisy but coherent rotational motion.

We account for this observation through a hydrodynamic approach, treating the nucleus as a highly viscous inclusion residing in a less viscous fluid of orientable filaments endowed with active stresses. Lowering actin contractility selectively by introducing blebbistatin at low concentrations drastically reduced the speed and coherence of the angular motion of the nucleus.

Time-lapse imaging of actin revealed a correlated hydrodynamic flow around the nucleus, with profile and magnitude consistent with the results of our theoretical approach. Coherent intracellular flows and consequent nuclear rotation thus appear to be an intrinsic property of cells.

Spontaneous actin dynamics in contractile rings. Networks of polymerizing actin filaments are known to be capable to self-organize into a variety of structures. For example, spontaneous actin polymerization waves have been observed in living cells in a number of circumstances, notably, in crawling neutrophils and slime molds.

During later stages of cell division, they can also spontaneously form a contractile ring that will eventually cleave the cell into two daughter cells. We present a framework for describing networks of polymerizing actin filaments, where assembly is regulated by various proteins.

It can also include the effects of molecular motors. We show that the molecular processes driven by these proteins can generate various structures that have been observed in contractile rings of fission yeast and mammalian cells. We discuss a possible functional role of each of these patterns. Objetivo: Recopilar la evidencia disponible sobre el uso del El leiomiosarcoma, en cambio, es un tumor maligno y agresivo de la musculatura lisa uterina.

Full Text Available Objetivos. Estudio de tipo experimental. Respuesta del sistema antioxidante en varones sanos, frente a hiperglicemia aguda inducida. Full Text Available Objetivo: determinar la respuesta del sistema antioxidante en varones sanos, frente a la hiperglicemia aguda inducida.

Uterine malformations are unusual findings in the clinical practice of gynecology. Statistics regarding this abnormality are flawed, and there is a lack of standardization of the pertinent terminology, besides difficulty in the diagnosis.

Starting in the 's, ultrasound became a procedure indispensable to the clinical practice in the field of tocogynecology, modifying concepts and procedures, and bringing an important contribution to this specialty. The advent of endocavitary transducers, amplitude and spectral color Doppler, as well as the increasing improvement in the imaging quality, has contributed to this progress.

Over the last ten years, much has been studied, published and discussed about the role of the three-dimensional ultrasonography. The authors review the topic and emphasize the importance of this method as a diagnostic modality.

Cell stiffness, contractile stress and the role of extracellular matrix. An, Steven S. Here we have assessed the effects of extracellular matrix ECM composition and rigidity on mechanical properties of the human airway smooth muscle ASM cell. Cell stiffness and contractile stress showed appreciable changes from the most relaxed state to the most contracted state: we refer to the maximal range of these changes as the cell contractile scope. The contractile scope was least when the cell was adherent upon collagen V, followed by collagen IV, laminin, and collagen I, and greatest for fibronectin.

Regardless of ECM composition, upon adherence to increasingly rigid substrates, the ASM cell positively regulated expression of antioxidant genes in the glutathione pathway and heme oxygenase, and disruption of a redox-sensitive transcription factor, nuclear erythroid 2 prelated factor Nrf2 , culminated in greater contractile scope.

These findings provide biophysical evidence that ECM differentially modulates muscle contractility and, for the first time, demonstrate a link between muscle contractility and Nrf2-directed responses.


2010, Número 12




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